Just a thought, I'm also not 100% certain on the function of these coils......would there be enough in-rush current to blow this fuse, if all the coils stopped working for a second, then suddenly started firing/charging while at approx 2000 RPM or higher under higher cylinder load?
My thinking is at idle or cranking, each coil fires slow enough with reduced load, or the succession between cylinder firing is slow. What if the crank signal was interrupted briefly while at a cruise RPM, then the coils paused if there was a loss of signal where the PCM could not command a firing, then unload the coils again but at a higher RPM, much higher than when cranking?
Another way to see this would be a gradual, lower intensity sine wave of charging cycles, then nothing, then a sudden, more rapid, large intensity of coil firings for each cylinder under load causing higher currents through the circuit.
Like turning a power amp off then back on with the volume cranked up.
That may be a whacked way to think why this fuse is blowing but could this be a loose or faulty crank sensor or another circuit that can shut down the coils when conditions are met?
What circuits can satisfy the PCM to pull spark, especially while running...oil pressure, ignition switch?
Something to happen quick enough that it wouldn't throw a code. I know that unplugging a coil then reattaching while the engine idling could blow a coil, but that might be a different set of circumstances.