With the V8's if one clogs/goes bad, you have to replace both because of how they are on the Y-Pipe. Unless of course you fab up your own and cut the factory y pipe,etc... Had to do both on my SS twice already (covered by the factory 8yr/80,000) where only one clogged but still hindered performance and made CEL come on.
First time my cats were bad it just made my CEL come on but performance was normal.
2nd time when that new set went bad, the one cat clogged and actually affected my trans shifting and bogged the truck down tremendously.