Recent plugs swapped around
How recent? Also, what plugs are in the engine now? Reason I ask, is the 4.2 is picky. Back in the day, almost any plug would work...but not with this motor.
How long has the fuel been in the tank? If a daily driver and replaced weekly or bi-monthly then likely not an issue.
Anytime I get random misfires like this, with known good coils and plugs, my goto can is BG44K. This stuff is not snake oil and works extremely well.
Another test I would run is place an envelope behind the tailpipe so the exhaust flow folds it over while holding one end against the outlet. Does the envelope "snap back" into the tailpipe or stayed folded over? If it snaps back then that points to the exhaust valve not fully seating, sometimes from carbon.
Second would be a vacuum gauge on the TB evap port and ensure the needle is steady.
Are the coils original or aftermarket or OE replacements? I went cheap about 2 years ago and grabbed the 6-pack off the web for about $150 and have since replaced most of them.